Top News in Singapore

New treatment options for colon cancer

ScienceDaily - - Reading time 2 mins - Share :
An existing chemotherapy drug used to treat leukemia could prevent and control the growth of colorectal tumors, scientists have discovered.
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Medical Xpress - New knowledge on EphB signaling may improve treatment of intestinal cancers

From Many, One

The Scientist - - Reading time 15 mins - Share :
Diverse mammals, including humans, have been found to carry distinct genomes in their cells. What does such genetic chimerism mean for health and disease?

My Mighty Mouse

The Scientist - - Reading time 13 mins - Share :
Personal drug regimens based on xenograft mice harboring a single patient’s tumor still need to prove their true utility in medicine.

Two degree Celsius climate change target 'utterly inadequate'

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The official global target of a two degree Celsius temperature rise is 'utterly inadequate' for protecting those at most risk from climate change, says an expert. The commentary presents a rare inside-view of a discussion at the Lima Conference of the Parties on the likely consequences of accepti...
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ScienceDaily - Two degree Celsius climate change target 'utterly inadequate'

Symptom ‘clusters’ plague sarcoma patients

Futurity / Karen Loh-NUS - - Reading time 1 mins - Share :
Sarcoma is a rare and debilitating cancer that can cause large, aggressive tumors. Patients with the disease experience symptoms such as pain, breathlessness, and nausea. Little research exists on the prevalence and severity of this symptom burden or medication usage among Asian patients. To add...

HBV exposure matures infants' immune systems

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A Singapore led study has shown that Hepatitis B Virus Infection (HBV) exposure increases the immune system maturation of infants, which may give a better survival advantage to counteract bacterial infection during early life. These findings radically modify the way that HBV vertical infection of...
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ScienceDaily - HBV exposure matures infants' immune systems

Mutations that may enable earlier diagnosis of colorectal cancer recurrence identified

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A multi-disciplinary team of doctors and scientists has characterized the genetic changes associated with the spread of colorectal cancer to the liver. Most patients are initially diagnosed with an early stage disease. However, a proportion of these patients will develop a recurrence of the cance...

South-East Asian haze increases risk of respiratory mortality

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Research has shown a significant association between haze events in South-East Asia and mortality rates caused by respiratory illness on the west coast of peninsular Malaysia.

Mechanobiology provides insight into disease and healing processes

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Researchers are gaining further insight into how the mechanical environment of cells drives fundamental cellular processes such as motility, growth and survival. These processes are integral to many clinical challenges, from cancer prognosis to wound healing and skin repair.

Scientists pioneer new drug regimen that reduces toxicities for renal cancer patients

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Conclusive results have been revealed in reducing toxicities for Asian patients with metastatic renal cell carcinoma or cancer that has spread beyond the kidney. The findings have revolutionized the standard protocol for patient management in NCCS with an attenuated-dose regimen of sunitinib for ...

Cyborg beetle research allows free-flight study of insects

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Cyborg insect research is enabling new revelations about a muscle used by beetles for finely graded turns. The remote-controlled beetles equipped with radio backpacks are showcasing the potential of miniature electronics in biological research.

Researchers find T cells target dengue virus at the skin infection site

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(Medical Xpress)—A team of researchers working in Singapore has found that human T cells actually target dengue viral infections in the skin, which is the normal infection site. In their paper published in the journal Science Translational Medicine, the team describes how they found that T cell...
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The Scientist - Dengue-Targeting T Cells Home to Skin

'Extinct' bird rediscovered: Last seen in 1941

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A scientific team has rediscovered a bird previously thought to be extinct. Jerdon's babbler (Chrysomma altirostre) had not been seen in Myanmar since July 1941, where it was last found in grasslands near the town of Myitkyo, Bago Region near the Sittaung River.

Finding psychological insights through social media

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Social media has opened up a new digital world for psychology research. Researchers are developing new methods of language analysis, and how social media can be leveraged to study personality, mental and physical health, and cross-cultural differences.

Systems to identify treatment targets for cancer and rare diseases

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In recent months, several national initiatives for personalized medicine have been announced, including the recently launched precision medicine initiative in the US, driven by rapid advances in genomic technologies and with the promise of cheaper and better healthcare. Significant challenges rem...

New weapon in war against flu pandemics and pneumonia

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Scientists have developed an antibody which boosts the survival chances for patients suffering from influenza and pneumonia. Proven effective in lab tests, the antibody is now being made suitable for use in humans. The scientists are also using the new antibody to develop a diagnostic kit which c...

Technology driving rise in abortions of girls in India

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Modernisation is not helping rebalance India's sex ratio. In fact, with 6 million fewer girls born between 2001 and 2011, it is making it worse

Octopus robot makes waves with ultra-fast propulsion

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Scientists have developed an octopus-like robot, which can zoom through water with ultra-fast propulsion and acceleration never before seen in human-made underwater vehicles. Most fast aquatic animals are sleek and slender to help them move easily through the water but cephalopods, such as the oc...

Researchers isolate genetic variants responsible for leprosy predisposition

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(Medical Xpress)—A team of researchers with members from institutions in China, the U.S. and Singapore has successfully isolated six genetic variants in people that confer a higher predisposition to infection by the bacteria that causes leprosy. In their paper published in the journal Nature Ge...

Birth method, gestation duration may alter infants' gut microbiota

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Environmental factors like mode of delivery and duration of gestation may affect how infants' gut bacteria mature, and that rate could help predict later body fat, international researchers have found.

Biomaterial coating raises prospect of more successful medical implants

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A novel, bacteria-repelling coating material that could increase the success of medical implants has been created. The material helps healthy cells 'win the race' to the medical implant, beating off competition from bacterial cells and thus reducing the likelihood of the implant being rejected by...
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Medical Xpress - Biomaterial coating raises prospect of more successful medical implants

Poo offers a peek at rare monkey’s diet

Futurity / Karen Loh-NUS - - Reading time < 1 mins - Share :
When an endangered species is too rare or too shy to study close-up, scientists have another option: getting millions of short DNA sequences from fecal samples. Fecal samples are of great value as they contain DNA from the diet, the gut lining of the host species, microbes, and parasites. A team,...

Breakthrough may impact flu vaccination

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An analysis of 10 years' worth of data on human influenza B viruses has shed new light on the pathogen which can cause the seasonal flu. Findings from this study could help make flu immunization programs more effective; by better targeting vaccines or by eventually eliminating one of the flu line...

Study details a link between inflammation and cancer

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A new study from MIT reveals one reason why people who suffer from chronic inflammatory diseases such as colitis have a higher risk of mutations that cause cancer. The researchers also found that exposure to DNA-damaging chemicals after a bout of inflammation boosts these mutations even more, fur...

U.S. or China: Who will invest more in medical R&D?

Futurity / Mark Michaud-Rochester - - Reading time 4 mins - Share :
The United States is steadily losing ground as the global leader in medical research. A new study tracked medical research activity from 1994 to 2014 in the US, Europe, Asia, Canada, and Australia, compiling data on funding by public and private sources, the creation of intellectual property, and...
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NPR / Richard Harris - U.S. Funding of Health Research Stalls As Other Nations Rev Up
ScienceDaily - Rate of investment in medical research has declined in U.S., increased globally

Attitudes, practices surrounding end of life care in ICUs vary among Asian physicians

ScienceDaily - - Reading time 2 mins - Share :
A majority of physicians surveyed throughout Asia reported almost always or often withholding life-sustaining treatment in end-of-life care for patients in hospital intensive care units when there is little chance of meaningful recovery, although attitudes and practice of end-of-life care varied ...

New therapeutic target for treatment of acute myeloid leukemia discovered

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New interactions between two molecules involved in acute myeloid leukemia (AML) have been found by scientists that may offer a new therapeutic target for cancer treatment. The scientists discovered that STAT3, a molecule which has the potential to cause cancer, associates with and regulates the l...

Chinese licorice used in traditional medicine can prevent diabetes

Naturalnews.com / By Jennifer Lilley - - Reading time 2 mins - Share :
(NaturalNews) For more than 4,000 years around the globe, parts of Glycyrrhiza plants (licorice) have been used as a natural sweetener as well as an herbal medicine to treat a range of health conditions. Its effectiveness is once again reinforced in findings recently published in...

Scientists discover gene critical for proper brain development

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Scientists at A*STAR's Institute of Medical Biology (IMB) and Institute of Molecular and Cellular Biology (IMCB) have identified a genetic pathway that accounts for the extraordinary size of the human brain. The team led by Dr Bruno Reversade[1]KATNB1, as an essential component in a genetic pathw...
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Medical Xpress - Healthy brain development balanced on edge of a cellular 'sword'
ScienceDaily - Gene critical for proper brain development discovered

Anti-diabetic drug springs new hope for tuberculosis patients

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A more effective treatment for tuberculosis (TB) could soon be available as scientists have discovered that metformin, a drug for treating diabetes, can also be used to boost the efficacy of TB medication without inducing drug resistance, scientists report.

Cancer patients testing drugs on mouse 'avatars'

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Scientists often test drugs in mice. Now some cancer patients are doing the same—with the hope of curing their own disease.

Uncovering one of humankind’s most ancient lineages

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Scientists have successfully discovered one of modern human’s ancient lineages through the sequencing of genes.  This is the first time that the history of humankind populations has been analysed and matched to Earth's climatic conditions over the last 200,000 years.

One in Five Superspreaders Trigger Majority of Viral Infections

Live Science - - Reading time 4 mins - Share :
This phenomenon occurs not only in human populations but also in animal populations, and involves both viral and bacterial infections.

Gene associated with an aggressive breast cancer uncovered

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A biomarker that is strongly associated with triple negative breast cancer, a highly aggressive carcinoma that often has early relapse and metastasis following chemotherapy, has been found by researchers. The newly identified biomarker, a gene called RASAL2, provides a target for developing new t...

Cannabis Biotech

The Scientist - - Reading time 9 mins - Share :
As medical marijuana businesses set up shop across the U.S., a handful of companies are taking the pharmaceutical route, guiding cannabis-derived drugs through clinical trials.

Gut microbiota influences blood-brain barrier permeability

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Our natural gut-residing microbes can influence the integrity of the blood-brain barrier, which protects the brain from harmful substances in the blood, a new study in mice shows. The blood-brain barrier is a highly selective barrier that prevents unwanted molecules and cells from entering the br...

Breakthrough discovery contributes to future treatment of multiple sclerosis, autoimmune inflammation

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An avenue for therapeutic intervention of multiple sclerosis may be ahead, thanks to new research. A team found that a new type of immune T helper cells named TH-GM cells play a crucial role in the immune system and pathogenesis of neuronal inflammation. The findings shed light on a possible new ...

Gut microbiota influences blood-brain barrier permeability

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A new study in mice, conducted by researchers at Sweden's Karolinska Institutet together with colleagues in Singapore and the United States, shows that our natural gut-residing microbes can influence the integrity of the blood-brain barrier, which protects the brain from harmful substances in the...

How livable are our cities? New measure developed

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An international study has devised a new measure for the 'livability' of major cities across the world. The Global Liveable Cities Index takes into account the sensibilities of ordinary working people from 64 cities, balancing work and play, environmental awareness, localism, globalism and many o...

Two-color barcodes: Dynamic duo to fight crime, cancer

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Miniature two-color barcodes have the potential to combat forgery and track cancerous cells, investigators say. Tiny rod-like single crystals that act as miniature dual-color barcodes have been synthesized by researchers. The researchers have demonstrated the potential of these barcodes for two v...

Novel solutions developed to fight obesity gene

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Individuals who are genetically predisposed to obesity may soon have a therapeutic solution to combat their condition. A research team has identified several potent inhibitors that selectively target FTO, the common fat mass and obesity-associated gene. These FTO-specific inhibitors pave the way ...
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Medical Xpress - Researchers develop novel solutions to fight the obesity gene